ProtocolOS

The rationale behind every eligibility criterion, before the protocol is final.

For protocol authors and review teams in oncology. ProtocolOS prepares the rationale; the team decides.

How it works

  1. Pick a trial or an ideaReview a posted protocol, or draft criteria for a new concept.
  2. Read the rationaleEach criterion shows its likely rationale, which arm it comes from where a drug link exists, and what similar trials used.
  3. Redraft, then decideRewrite the criterion, watch the deterministic checks update as you type, then record the team's reason.
Finishing a trialReview an existing protocolOpen a posted oncology protocol. Each lab, ECOG, washout and condition criterion gets its likely rationale (inferred unless the protocol states it), the arm whose drugs are linked to it where a drug link exists, the values similar trials used, and the deterministic verifier's verdict on any other limit you propose.Open the reviewCreate criteria from an ideaDraft criteria for a new conceptDescribe the condition, drugs and setting. ProtocolOS proposes values only from verified precedents, then critiques its own draft; otherwise it says Insufficient evidence.Start a draft

Four worked examples and the draft examples open at once. Adding another trial, drafting a new idea and model answers in the Ask tab use your own OpenAI or Anthropic API key; this server has no model key of its own.

Public sources only. Rationale in non-public sources (preclinical toxicology, internal development data, regulator correspondence) cannot be seen by ProtocolOS.

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